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NEW QUESTION: 1
Which of the following is true regarding extent of absorption of drugs?
A. Drugs which are too hydrophilic are not soluble enough to cross the water layer adjacent to the cell
B. Drugs which are too lipophilic cannot cross the lipid cell membrane
C. After oral ingestion of drugs, the absorption of drug may be incomplete
D. P-glycoprotein is an efflux transporter which is present in the enterocytes and it enhances the absorption of drug
E. Grape juice activates P-glycoprotein leading to substantial inhibition of absorption of drugs
Answer: C
Explanation:
Explanation
It is not necessary that all the drugs get completely absorbed after oral administration. Most of them are incompletely absorbed. The extent of absorption varies from 5 to less than 100 % with oral ingestion of drugs.
Drugs which are too hydrophilic like atenolol are incompletely absorbed because the drug cannot cross the lipid membrane due to high hydrophilic nature of the drug. Similarly, drugs which are too lipophilic like acyclovir are not soluble enough to cross the water layer adjacent to the cell. P-glycoprotein is an efflux transporter which is present in the enterocytes and it inhibits absorption of drug. It is also known as export transporter or reverse transporter. It has many drugs as its substrate. Grape juice in fact inhibits P-glycoprotein in the intestine thereby decreasing the efflux of drug from the cells by P-glycoprotein. Thus ingestion of grape juice may lead to significantly increased absorption of the drug.

NEW QUESTION: 2
TSM's new support for z/OS provides which of the following?
A. Data mobility between zOS and PASE
B. Direct access to open systems tape
C. Ability to share mainframe tape withthe open systems environment
Answer: C
Explanation:
TSM for z/OS Media: *Leverages a customers current investment in TSM
-
Preserve stored archive (and backup) data
-
Minimize retraining by allowing continuation of existing TSM administrative tasks
-
Utilize existing TSM client software *Supports existing storage hardware used by TSM z/OS servers *Allows continued sharing of tape library resource (drives and media) under z/OS *Provides an easy migration path from z/OS server
-
avoiding time-consuming migration of data from existing storage pools
*Leverage potential strengths of z/OS and open systems
-
Exploit superior tape infrastructure and management on z/OS
-
Reduce CPU usage by TSM on z/OS
-
Lower cost of running TSM on open systems
Reference: IBM Redbook,IBM Tivoli Storage Manager for z/OS Media

NEW QUESTION: 3
Which feature or value must be configured to enable EIGRPv6?
A. Router ID
B. Remote AS
C. Network statement
D. Shutdown feature
Answer: A
Explanation:
The configuration of EIGRP for IPv6 has some restrictions; which are:
The interfaces can be directly configured with EIGRP for IPv6, without the use of a global IPv6 address.
There is no network statement in EIGRP for IPv6.
The router ID needs to be configured for an EIGRPv6 protocol instance before it can run.
EIGRP for IPv6 has a shutdown feature. Ensure that the routing process is in "no shut" mode in order to run the protocol.
https://www.cisco.com/c/en/us/support/docs/ip/enhanced-interior-gateway-routing-protocol- eigrp/113267-eigrp-ipv6-00.html

NEW QUESTION: 4
Which statement below BEST describes non-functional testing?
A. Testing system attributes, such as usability, reliability or maintainability.
B. The process of testing an integrated system to verify that it meets specified requirements.
C. Testing without reference to the internal structure of a system.
D. The process of testing to determine the compliance of a system to coding standards.
Answer: B

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